Last edited by Mikagor
Friday, May 15, 2020 | History

1 edition of Environmental Epigenomics in Health and Disease found in the catalog.

Environmental Epigenomics in Health and Disease

Epigenetics and Disease Origins

by Randy L. Jirtle

  • 314 Want to read
  • 29 Currently reading

Published by Springer Berlin Heidelberg, Imprint: Springer in Berlin, Heidelberg .
Written in English

    Subjects:
  • Gene Function,
  • Biomedicine,
  • Oncology,
  • Cancer,
  • Human genetics,
  • Research,
  • Medical genetics,
  • Medicine

  • About the Edition

    Exposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, cocaine, radiation, tobacco smoke, and xenoestrogens. Particular emphasis is placed on the consequences of environmental exposures during development on epigenetic reprogramming that influences adult disease pathogenesis. Health outcomes associated with these exposures include autoimmune disorders, neurodevelopmental disorders, and cancer. Importantly, dietary supplements and drugs can modify the epigenetic effects induced by these agents, thereby reducing their toxicological impact. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic processes and developmental programming.

    Edition Notes

    Statementedited by Randy L Jirtle, Frederick L. Tyson
    SeriesEpigenetics and Human Health
    ContributionsTyson, Frederick L., SpringerLink (Online service)
    Classifications
    LC ClassificationsRB155-155.8, QH431
    The Physical Object
    Format[electronic resource] :
    PaginationXV, 302 p. 41 illus., 34 illus. in color.
    Number of Pages302
    ID Numbers
    Open LibraryOL27036724M
    ISBN 109783642233807

    The book is sub-divided into three sections and 13 chapters. while section C will provide examples for the impact of epigenomics in human health and disease. The lecture course is primarily.   The objective of this book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, Pages:

    Book Chapter: Faulk C, Dolinoy DC. Complex phenotypes: epigenetic manifestation of environmental exposures. In: Jirtle RL, Tyson FL, eds. Environmental Epigenomics in Health and Disease: . Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and .

      Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and Format: Hardcover. book provides an introduction to an in-depth understanding of the role of epigenetics in the mechanisms of inheritance and interaction with the environment. The chapters also describe the role of epige-netics in health and disease. Finally, the book File Size: KB.


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Environmental Epigenomics in Health and Disease by Randy L. Jirtle Download PDF EPUB FB2

In this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, a number of leading investigators in the field of epigenetics discuss patterns of epigenomic. The objective of this book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular.

The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, Manufacturer: Springer.

The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, is to give readers an overview of how environmental exposures Manufacturer: Springer. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates.

This book chapter aims to provide a gentle introduction to the vast universe of available software tools for the analysis of Epigenomics data. An epigenomic epidemiologic study may be used to investigate. Request PDF | Environmental Epigenomics in Health and Disease: Epigenetics and Complex Diseases | The capacity of the epigenome to interpret both internal and external stimuli and alter expression.

The Keystone symposium on ‘Environmental Epigenomics and Disease Susceptibility' was held in late March at the Grove Park Inn Resort in Asheville, North Carolina, USA. The meeting helped to Cited by: Epigenomics in Health and Disease.

discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. Jirtle, R., Skinner, M. Environmental epigenomics and disease susceptibility.

Nat Rev Genet 8, – ( International Journal of Environmental Research and Public Health ()Cited by: Meet Editor-in-Chief Michael K. Skinner and the rest of the Environmental Epigenetics editorial board.

Find out more about their background and specialist areas of research. Skinner's introductory. Michele Meisner, David M. Reif, in Systems Biology in Toxicology and Environmental Health, Epigenomics. Epigenomics studies differential gene expression triggered by chemical reactions or.

The Environmental Epigenomics and Disease Group has developed novel methods that identify SNPs and DNA methylation changes in environmentally responsive enhancers (Figure 1) and. Understanding Epigenomics: How Environmental and Social Factors Affect Our Genes’ 'Instruction Book' Faculty members at the University of Michigan School of Public Health are leading the way in.

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x mm. Language: English. Brand New Book. Get this from a library. Environmental epigenomics in health and disease: epigenetics and complex diseases. [Randy L Jirtle; Frederick L Tyson;] -- The capacity of the epigenome to interpret both. According to the WHO (World Health Organization), more than 13 million deaths annually are due to environmental causes and as much as 24% of disease is caused by exposures that can be averted.

The objective of this two volume book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer.

Grantees at Beth Israel Deaconess Medical Center used epigenetics to define the link between environmental exposure to smoke, mercury, and lead, and reproductive outcomes, such as. Free 2-day shipping. Buy Epigenetics and Human Health: Environmental Epigenomics in Health and Disease: Epigenetics and Complex Diseases (Paperback) at nd: Randy L Jirtle; Frederick L Tyson.

Environmental Epigenetics and Disease Risk. In this review, we have examined the current literature and expert opinions on environmental epigenetics, a term that is narrowly defined as how epigenetics Cited by: Get this from a library!

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